A Boeing 777 aircraft crashed on the runway at San Francisco International Airport on Saturday morning, killing at least two people and injuring dozens of others, San Francisco Fire Chief Joanne Hayes-White said.
Officials said that 182 people on board the flight were taken to local hospitals, and 49 are in critical condition. A total of 123 were uninjured.
The Asiana Airlines Flight 214 from Seoul, Korea was coming in for a landing when the tail end of the plane slammed into a rocky berm or sea wall near the edge of the San Francisco Bay and the runway, according to witness reports. Hayes-White said the plane originated in Shanghai, China.
The plane then appeared to skid off the runway and rested in a dirt right-of-way. The fuselage caught fire.
About 307 people were on the aircraft, including 16 crew members, Hayes-White said.
Patients arrived in hospitals with burns, fractures, head injuries, spinal compressions and injuries requiring immediate surgery.
Facebook Chief Operating Officer Sheryl Sandberg said on Twitter that she was supposed to be on the flight.
"Taking a minute to be thankful and explain what happened. My family, colleagues Debbie Frost, Charlton Gholson and Kelly Hoffman and I were originally going to take the Asiana flight that just crash-landed. We switched to United so we could use miles for my family's tickets. Our flight was scheduled to come in at the same time, but we were early and landed about 20 minutes before the crash. ... Serious moment to give thanks," she wrote.
A National Transportation Safety Board (NTSB) spokeswoman said three inspectors were traveling to the Bay Area from Los Angeles. Teams will be flying out from Washington D.C. And will be looking at all possible reasons for the crash, she said.
Airport officials had initially shut down the airport, but by 3:45 p.m. two runways were reopened. Rosemary Barnes, a spokeswoman for San Jose International Airport, said the airport had accepted 17 flights from SFO and was expected to take 10 other flights.